Heterotopic Ossification (H.O.)

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Understanding Heterotopic Ossification (H.O.)

Heterotopic ossification (H.O.) is a benign condition in which bone forms abnormally in soft tissues such as muscles, tendons, or ligaments—often near joints. This abnormal bone growth can lead to pain, stiffness, reduced range of motion, and functional limitations.

H.O. most commonly develops after trauma, orthopedic surgery (such as hip or knee replacement), spinal cord injury, or neurological injury. While not cancerous, heterotopic ossification can significantly impact mobility and quality of life if left untreated.

At Radiant Cancer Care, radiation therapy may be considered in select cases of heterotopic ossification, most commonly as a preventive treatment following surgery or injury when the risk of abnormal bone formation is high.


Common Symptoms of Heterotopic Ossification

Symptoms of H.O. vary depending on location and severity and may include:

  • Pain or tenderness near a joint
  • Swelling or warmth in the affected area
  • Progressive stiffness or reduced range of motion
  • Difficulty walking or performing daily activities
  • Palpable hard mass near soft tissue
  • Functional limitations following surgery or injury

Early recognition is important, as preventive treatment is most effective before significant bone formation occurs.


Diagnosis: What to Expect

Diagnosing heterotopic ossification typically involves:

  • Medical history & physical exam: Review of recent surgery, trauma, or neurological injury
  • Imaging tests: X-rays, CT scans, or bone scans to detect abnormal bone formation
  • Orthopedic consultation: Evaluation of joint function and mobility
  • Risk assessment: Identification of patients at higher risk for recurrence

Radiation therapy is usually considered before or shortly after surgery, or early in the disease process.

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Treatment Options for Heterotopic Ossification

Treatment for H.O. depends on timing, severity, and symptoms. In select patients, low-dose radiation therapy may be used as a preventive or supportive treatment.

Radiation Therapy (Preventive & Select Cases)

Radiation therapy may be considered:
  • To prevent heterotopic ossification following orthopedic surgery
  • For patients with a history of recurrent H.O.
  • When nonsteroidal anti-inflammatory medications are not suitable
  • As part of a coordinated orthopedic care plan
At Radiant Cancer Care, radiation therapy for H.O. is:
  • Delivered using carefully planned, low-dose protocols
  • Targeted precisely to areas at risk for abnormal bone growth
  • Designed to minimize side effects
Coordinated closely with orthopedic surgeons and referring providers

Radiant Cancer Care Offers:

Based out of Rancho Mirage, Radiant Cancer Care serves residents of the following areas:

Why Choose Radiant Cancer Care To Treat Your Condition?

Choosing a cancer care provider is an important decision. At Radiant Cancer Care, we are committed to delivering:

Patient-Centered Care

We take the time to listen, educate, and support you and your family throughout your treatment journey.

Advanced Radiation Technology

We use modern treatment planning and delivery systems to maximize effectiveness and reduce side effects.

Multidisciplinary Collaboration

We work closely with primary care physicians, urologists, medical oncologists, and support specialists to ensure continuity of care.

Support Throughout Your Journey

From initial consultation to treatment completion and follow-up care, our team is here to answer questions and help you feel confident in your care.

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Caring Experts Who Are Here for You

Ted Ling, MD and Carolyn Barnes, MD have dedicated their careers to helping patients through every stage of cancer care.

Meet Our Radiation Oncologists

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